HuagongsheHuagongshe Chemistry Print Report · For research reference only
Erythromycin → 3-O-Methylmycarose
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Erythromycin | HCID 12560 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 3-O-Methylmycarose | HCID 5460588 | 97% |
Reaction Steps
Erythromycin A (Merck Index, 10th Edition Entry No. 3624) (50g) was dissolved in 1N aqueous hydrochloric acid (70 mL) and water (500 mL) and the mixture subjected to liquid-liquid extraction using diethyl ether for 99 h. The ether extract was evaporated to dryness to give L-cladinose (11.7 g, 97%) as a colorless viscous oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04962146 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-9bd319bce50f4dec8058b7266ed1858e |
| Source note | uspto-grants-1990_10 |