HuagongsheHuagongshe Chemistry Print Report · For research reference only
Resorcinol → Methyl 2-(3-hydroxyphenoxy)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Resorcinol | HCID 5054 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 2-bromopropionate | HCID 95576 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | Methyl 2-(3-hydroxyphenoxy)propanoate | HCID 10703027 | — |
Reaction Steps
A mixture of resorcinol (11.0 g), methyl 2-bromopropanoate (20 g), potassium carbonate (27.6 g) and methyl ethyl ketone (120 mL) was heated under reflux for 5 hours. The reaction mixture was filtered, evaporated and the residue was separated by chromatography. Elution with 1:3 ethyl acetate/hexane afforded the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04962203 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-bc9a170e0a024eb1816d1840d483039c |
| Source note | uspto-grants-1990_10 |