Benzene → HCID 22163145, compound

HRID 1088509Notes

Reaction equation

HRID 1088509 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=O)[CH3:2].[C:10]([C:15]1[CH:16]=[C:17]([CH:19]=[CH:20][CH:21]=1)[NH2:18])([O:12][CH2:13][CH3:14])=[O:11].C1C=CC=CC=1>O>[CH3:2][C:1](=[N:18][C:17]1[CH:19]=[CH:20][CH:21]=[C:15]([C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH:16]=1)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

5

Reactant 3

HCID 241BenzeneHCID 7410AcetophenoneHCID 11400Ethyl 3-aminobenzoate

Product 1

HCID 22163145HCID 22163145, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of acetophenone (95 ml), m-carbethoxy aniline (75 ml), benzene (150 ml) was refluxed in the presence of molecular sieve (50 g) with continuous removal of water. The crude product was distilled under reduced pressure to give N-(α-methyl benzylidene)-m-carbethoxyaniline (XIII). XIII had a boiling point of 205° C. at 0.1 millimeter.

Workup

  1. distillationThe crude product was distilled under reduced pressure

Sources & evidence

ORD record
ord-da9e7ada385e4e0a8d04f05d31129eb4
Source dataset
uspto-grants-1990_10
Patent number
US04962234

Reaction notes

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