1H-Indene, (1-methylethyl)- → HCID 23700053, compound

HRID 1088539Notes

Reaction equation

HRID 1088539 reaction equation
C([Li:5])CCC.[CH:6]([CH:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:11]=[CH:10]1)([CH3:8])[CH3:7]>CCCCCC>[CH:6]([C-:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:11]=[CH:10]1)([CH3:8])[CH3:7].[Li+:5]

Participants

4

Reactant 2

HCID 2364061H-Indene, (1-methylethyl)-HCID 178418339Butyllithium

Product 1

HCID 23700053HCID 23700053, compoundYield 89%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent2×

Procedure

All operations are performed under an inert atmosphere and with dry, degassed solvents. A solution of 20.0 ml (32.0 mmoles) of 1.6 M butyl lithium in hexane is added to a stirred solution of 5.06 g (32.0 mmoles) of 1-isopropylindene in 100 ml of hexane at room temperature. A white precipitate appeared after 30 minutes at room temperature. Filtration after 2 days at room temperature produces 2.8 g of white solid product. The filtrate is concentrated to 20 ml and, after standing at room temperature another week, an additional 1.9 g of product is recovered for a total of 4.7 g (89 percent yield).

Workup

  1. customwith dry
  2. customdegassed solvents
  3. filtrationFiltration after 2 days at room temperature

Sources & evidence

ORD record
ord-25562c7254f0425998aac749fa186469
Source dataset
uspto-grants-1990_10
Patent number
US04962253

Reaction notes

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