Valeryl chloride → HCID 14822884, compound

HRID 1088678Notes

Reaction equation

HRID 1088678 reaction equation
Cl.[NH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[C:11]3[NH:18][C:17](=[O:19])[NH:16][C:12]3=[N:13][C:14]=2[CH3:15])=[CH:5][CH:4]=1.[C:20](Cl)(=[O:25])[CH2:21][CH2:22][CH2:23][CH3:24]>>[CH2:21]([C:20]([NH:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[C:11]3[NH:18][C:17](=[O:19])[NH:16][C:12]3=[N:13][C:14]=2[CH3:15])=[CH:5][CH:4]=1)=[O:25])[CH2:22][CH2:23][CH3:24]

Participants

3

Reactant 2

HCID 61186Valeryl chlorideHCID 20060128HCID 20060128, compound

Product 1

HCID 14822884HCID 14822884, compound

Procedure

[I; Ar 4-CH3 (CH2)3CONHC6H4, R1 and R3H, R5 =CH3 ]was prepared from 3 g 6-(4-aminophenyl)-1,3-dihydro-5-methyl-2H-imidazo[4,5-b]pyridin-2-one hydrochloride and 1.86 ml valeryl chloride according to the procedure of Example 7, and was obtained (1.16 g) as a colorless solid, m.p. above 300° C. when recrystallized from ethanol.

Workup

  1. customwas obtained (1.16 g) as a colorless solid, m.p. above 300° C. when
  2. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-fb061385ef984637ac1b4fc051c8f906
Source dataset
uspto-grants-1990_10
Patent number
US04963561

Reaction notes

Loading…