Water → HCID 53765282, compound

HRID 1088684Notes

Reaction equation

HRID 1088684 reaction equation
C(CC[N:5]1[C:9](=[O:10])[CH2:8][C:7]2([CH2:15][CH2:14][C:13]([CH2:19][CH2:20][CH3:21])([CH2:16][CH2:17][CH3:18])[CH2:12][CH2:11]2)[C:6]1=[O:22])#N.CNCCCN.O>C1(C)C=CC=CC=1>[CH2:19]([C:13]1([CH2:16][CH2:17][CH3:18])[CH2:14][CH2:15][C:7]2([C:6](=[O:22])[NH:5][C:9](=[O:10])[CH2:8]2)[CH2:11][CH2:12]1)[CH2:20][CH3:21]

Participants

5

Reactant 3

HCID 962WaterHCID 80511N-Methyl-1,3-propanediamineHCID 15634104HCID 15634104, compound

Product 1

HCID 53765282HCID 53765282, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To a solution of toluene and 4,4 dipropylcyclohexane 1 carboxy 1 acetic acid anhydride (1 equivalent) was added 3 methylaminopropylamine (1.05 equivalents). The reaction mixture was heated at reflux using a Dean Stark trap. Following collection of water (1 equivalent), the reaction mixture was cooled to room temperature and concentrated under reduced pressure. The residue was used without further purification.

Workup

  1. temperatureThe reaction mixture was heated
  2. temperatureat reflux
  3. concentrationconcentrated under reduced pressure
  4. customThe residue was used without further purification

Sources & evidence

ORD record
ord-c73eeba5729f4f1da3d087ea3bdf12e0
Source dataset
uspto-grants-1990_10
Patent number
US04963557

Reaction notes

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