HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Benzo[b]thiophene-5-ol, 2,3-dihydro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Triethylsilane | HCID 12052 | — |
| Reactant | Benzo[b]thiophen-5-ol | HCID 12203499 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Product | Benzo[b]thiophene-5-ol, 2,3-dihydro- | HCID 11367101 | — |
Reaction Steps
Scheme I depicts the preparation of the simplest member (2) of the invention, that is where R4 and R6 are both hydrogen. Triethylsilane is reacted with 5-hydroxybenzothiophene in a suitable solvent, e.g, trifluoroacetic acid (TFA) to yield the 5-hydroxy-2,3-dihydrobenzothiophene. ##STR4##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04963580 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-aaf8dab87dc744f295cf771677efde33 |
| Source note | uspto-grants-1990_10 |