HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl acetate hexane → HCID 22161963, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Reactant | HCID 22161965 | HCID 22161965 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 22161963 | HCID 22161963 | 85.8% |
Reaction Steps
A solution of 6-allyl-2,3-dihydrobenzothiophene (95 mg, 0.49 mmole) in 10 mL absolute ethanol was hydrogenated at 40 psi over 20 mg 10% Pd/C at room temperature overnight. TLC (90/10, hexane/EtOAc) indicated the reaction to be complete. The catalyst was filtered off through a celite pad and the filtrate concentrated down to afford 96 mg crude product as an oil. Purification by flash chromatography (90/10, hexane/EtOAc) afforded 75 mg white solids mp 58°-60° C. (78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04963580 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-840ed4cbd7704e2b8c2f736bd95d9421 |
| Source note | uspto-grants-1990_10 |