Hydrochloric Acid → HCID 14835753, compound

Participants

Reaction Conditions

Reaction Steps

3-Methoxycarbonylcinnamyl chloride (24 g) was dissolved in dry tetrahedrofuran and then this solution added to lithium tri-tert-butoxyaluminohydride (63.5 g) dissolved in tetrahydrofuran (250 ml) at -78° C. The resultant clear solution was stirred at -78° C. for 30 minutes then it was added to ice and 2 M hydrochloric acid (750 ml). The two phase mixture was extracted 4 times with dichloromethane. After drying the dichloromethane was evaporated to yield the title compound as a pale yellow oil.

Provenance & Evidence