HRID1088769

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID75994

1-Benzylpiperazine

C11H16N2

结构：CC1=C(c2cccc(C(F)(F)F)c2)n2ncc(C#N)c2N(C(=O)CCl)C1

HCID15101085

未命名化合物

PRODUCTS

生成物

结构：CC1=C(c2cccc(C(F)(F)F)c2)n2ncc(C#N)c2N(C(=O)CN2CCN(Cc3ccccc3)CC2)C1.Cl.Cl

HCID131716668

未命名化合物

PROCEDURE

实验过程

The above compound was prepared by the reaction of N-benzylpiperazine with the compound of Example 10 by the methods of Example 16 then 77, mp 204°-206° C.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-bc21cb235e694dd7983a632c7ea2d5d6
来源数据集: uspto-grants-1990_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04963553
来源说明: uspto-grants-1990_10

反应 SMILES

[CH2:1]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:14][CH2:15][C:16]([N:18]1[CH2:23][C:22]([CH3:24])=[C:21]([C:25]2[CH:30]=[CH:29][CH:28]=[C:27]([C:31]([F:34])([F:33])[F:32])[CH:26]=2)[N:20]2[N:35]=[CH:36][C:37]([C:38]#[N:39])=[C:19]12)=[O:17]>>[ClH:14].[ClH:14].[CH3:24][C:22]1[CH2:23][N:18]([C:16](=[O:17])[CH2:15][N:11]2[CH2:12][CH2:13][N:8]([CH2:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[CH2:9][CH2:10]2)[C:19]2[N:20]([N:35]=[CH:36][C:37]=2[C:38]#[N:39])[C:21]=1[C:25]1[CH:30]=[CH:29][CH:28]=[C:27]([C:31]([F:32])([F:33])[F:34])[CH:26]=1