8-Methylquinoline → 8-(Bromomethyl)quinoline

Participants

Reaction Steps

8-Methylquinoline (4.02 g) was dissolved in carbon tetrachloride (40 ml), and N-bromosuccinimide (5.98 g) and benzoyl peroxide (0.15 g) were added to the solution, and the mixture was heated and refluxed for 3 hours. After filtering off the insoluble matter, the filtrate was concentrated. The resultant residue was recrystallized from ligroin to give 8-bromomethylquinoline (3.60 g).

Provenance & Evidence