Potassium Carbonate → HCID 22161789, compound

Participants

Reaction Steps

To a solution of 8-(5-fluoro-6-methoxy-2-benzimidazolyl)thiomethyl-1-ethyl-4-acetyloxymethyl-1,2,3,4-tetrahydroquinoline (2.55 g) in methanol (20 ml) was added a saturated aqueous solution of potassium carbonate (10 ml) and the mixture was stirred for 1 hour at room temperature. The reaction mixture was extracted with dichloromethane and dried. The solvent was distilled off to give 8-(5-fluoro-6-methoxy-2-benzimidazolyl)thiomethyl-1-ethyl-4-hydroxymethyl-1,2,3,4-tetrahydroquinoline (1.74 g).

Provenance & Evidence