4-Chlorobenzenesulfonyl chloride → HCID 14820515, compound

HRID 1088834Notes

Reaction equation

HRID 1088834 reaction equation
Cl.Cl.[NH2:3][CH:4]1[CH2:12][C:11]2[C:6](=[CH:7][CH:8]=[C:9]([NH2:13])[CH:10]=2)[CH2:5]1.[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([S:21](Cl)(=[O:23])=[O:22])=[CH:17][CH:16]=1>>[NH2:13][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[CH2:5][CH:4]([NH:3][S:21]([C:18]1[CH:19]=[CH:20][C:15]([Cl:14])=[CH:16][CH:17]=1)(=[O:23])=[O:22])[CH2:12]2

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 221619732,3-Dihydro-1H-indene-2,5-diamine--hydrogen chloride (1/2)

Product 1

HCID 14820515HCID 14820515, compound

Procedure

2,5-Diaminoindan dihydrochloride and 4-chlorophenylsulfonyl chloride are treated similarly as in Reference example 1 - (4) to give 5-amino-2-(4-chlorophenyl)sulfonylaminoindan.

Sources & evidence

ORD record
ord-e314ceaf6cf5412d953c245e1f6a82fa
Source dataset
uspto-grants-1990_10
Patent number
US04963587

Reaction notes

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