HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-(3,4-Dimethoxyphenyl)pentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-(3,4-Dimethoxyphenyl)-5-oxovaleric acid | HCID 2758470 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Catalyst | Mercuric Chloride | HCID 24085 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 5-(3,4-Dimethoxyphenyl)pentanoic acid | HCID 240459 | — |
Reaction Steps
A mixture containing 37.6 g of the product obtained in Example 38 and 64 g of zinc turnings (treated with a solution of HgCl2), 55 ml of toluene and 220 ml of conc. hydrochloric acid was refluxed for 1 h. Toluene phase was separated and evaporated in vacuo. The residue was crystallized from toluene-petroleum ether, yield 11.5 g (32%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04963590 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-8888cec068324f3cb539a7efe923d6fd |
| Source note | uspto-grants-1990_10 |