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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1088875Generated: November 2, 2026

Acetophenone → 1-Phenyl-3-(3-methoxy-4-hydroxy-5-trifluoromethylphenyl)prop-2-en-1-one

https://huagongshe.com/reaction/1088875

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetophenoneHCID 7410—
Reactant4-Hydroxy-3-methoxy-5-(trifluoromethyl)benzaldehydeHCID 19389199—
Product1-Phenyl-3-(3-methoxy-4-hydroxy-5-trifluoromethylphenyl)prop-2-en-1-oneHCID 54057087—

Reaction Steps

The procedure described in Example 8 was repeated using 1.7 g of 3-methoxy-4-hydroxy-5-trifluoromethylbenzaldehyde and 1.0 g of acetophenone. Yield 1.1 g (45%), m.p. 166°-168° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04963590
Source datasetuspto-grants-1990_10
ORD IDord-bd8abb4cbe4b43b0b9131ebd70b8687c
Source noteuspto-grants-1990_10