HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyano-N,N-dimethylacetamide → N,N-Dimethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyano-N,N-dimethylacetamide | HCID 251143 | — |
| Reactant | 3,4-Dihydroxy-5-nitrobenzaldehyde | HCID 5748957 | — |
| Reactant | Piperidine, acetate | HCID 9793820 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N,N-Dimethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide | HCID 54424215 | — |
Reaction Steps
A solution containing 1.83 g of 3,4-dihydroxy-5-nitrobenzaldehyde, 1.2 g of N,N-dimethylcyanoacetamide and catalytic amount of piperidine acetate in 40 ml of dry ethanol was refluxed over night. Yield 1.1 g (40%), m.p. 183°-185° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04963590 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-95e05ae9ecba4669a6b0dd9e009632f8 |
| Source note | uspto-grants-1990_10 |