Acetylacetone → 3-(3,4-Dihydroxy-5-trifluoromethylbenzylidene)-2,4-pentanedione

HRID 1088886Notes

Reaction equation

[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([C:11]([F:14])([F:13])[F:12])[C:9]=1[OH:10])[CH:5]=O.[CH3:15][C:16](=[O:21])[CH2:17][C:18](=[O:20])[CH3:19]>>[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([C:11]([F:14])([F:13])[F:12])[C:9]=1[OH:10])[CH:5]=[C:17]([C:16](=[O:21])[CH3:15])[C:18](=[O:20])[CH3:19]

Participants

Reactant 2

HCID 31261Acetylacetone

HCID 193891883,4-Dihydroxy-5-(trifluoromethyl)benzaldehyde

Product 1

HCID 189903903-(3,4-Dihydroxy-5-trifluoromethylbenzylidene)-2,4-pentanedione

Procedure

The procedure described in Example 7 was repeated using 2.06 g of 3,4-dihydroxy-5-trifluoromethyl-benzaldehyde and 1.00 g of 2,4-pentanedione. Yield 1.39 g (45%), m.p. 198°-205° C.

Sources & evidence

ORD record: ord-8346ab4a9c134d9e986af9361a894751
Source dataset: uspto-grants-1990_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04963590

Reaction notes

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