HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminoacetanilide → 7-[3(4-Acetamidophenyl)thioureido]-3,4-dihydro-2(1H)quinolone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminoacetanilide | HCID 31230 | — |
| Reactant | 7-isothiocyanato-3,4-dihydroquinolin-2(1H)-one | HCID 15719019 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 7-[3(4-Acetamidophenyl)thioureido]-3,4-dihydro-2(1H)quinolone | HCID 15719020 | — |
Reaction Steps
A solution containing 0.8 g of 7-isothiocyanato-3,4-dihydro-2(1H)quinolone and 0.59 g of 4-acetamidoaniline in 10 ml of THF was stirred for 5 h at room temperature. The product was filtered, dried and used as such to the next step. Yield 0.45 g (32%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04963677 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-eb750161276e45c4b9a1cefd5263a14e |
| Source note | uspto-grants-1990_10 |