Sodium Hydroxide → HCID 23673130, compound

HRID 1089047Notes

Reaction equation

HRID 1089047 reaction equation
[CH3:1][N:2]1[C:10]([CH3:11])=[CH:9][C:8](=[O:12])[C:4]([C:5]([OH:7])=[O:6])=[C:3]1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[OH-].[Na+:20]>CO>[CH3:1][N:2]1[C:10]([CH3:11])=[CH:9][C:8](=[O:12])[C:4]([C:5]([O-:7])=[O:6])=[C:3]1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[Na+:20]

Participants

4

Reactant 2

HCID 14798Sodium Hydroxide2×HCID 14075272HCID 14075272, compound

Product 1

HCID 23673130HCID 23673130, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1.69 g of 1,6-dimethyl-2-phenyl-4-oxonicotinic acid is suspended in approximately 50 ml of methanol. NaOH pellets (0.305 g) are added with stirring. After both the acid and the sodium hydroxide dissolve the solution is evaporated to dryness in vacuo. Sodium 1, 6-dimethyl-2-phenyl-4-oxonicotinate is then isolated as a glossy, somewhat hydroscopic solid. Yield=1.6 g.

Workup

  1. customis evaporated to dryness in vacuo

Sources & evidence

ORD record
ord-7a1712fa79854f1f969373b366356a61
Source dataset
uspto-grants-1990_10
Patent number
US04964896

Reaction notes

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