HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 14075363, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 22159883 | HCID 22159883 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | HCID 14075363 | HCID 14075363 | — |
Reaction Steps
2.7 g. of crude ethyl 1,2,6-trimethyl-5-(4'-bromophenyl)-4-oxonicotinate was suspended in 27 g. of 5% NaOH in 1:1 methanol/water. The reaction mixture was refluxed for 21/2 hours, cooled and acidified. Filtration of the resulting solid provided 2.2 g of 1,2,6-trimethyl-5-(4-bromophenyl)-4-oxonicotinic acid. m.p.=228°-230° C. (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04964896 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-ad5b6a6e825442048db532a57bc3e175 |
| Source note | uspto-grants-1990_10 |