HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Acetylpyridine → (1R)-1-(Pyridin-2-yl)ethan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Acetylpyridine | HCID 9589 | — |
| Reactant | 2-Acetylpyridine | HCID 14286 | — |
| Product | (1R)-1-(Pyridin-2-yl)ethan-1-ol | HCID 642847 | — |
Reaction Steps
Example 1 was repeated except that 3-acetylpyridine used in Example 1 was replaced by 2-acetylpyridine to obtain (R)-1-(2-pyridyl)ethanol. According to a high-speed liquid chromatography using an optical resolution column (CHIRAL CEL OB made by Daicel K. K.), its optical purity was 95% ee or higher.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04965018 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-0fe3467a980b413981ad74be4d4d7ad8 |
| Source note | uspto-grants-1990_10 |