Ethanol → 1-N-Cbz-4-hydroxy-beta-proline

HRID 108912Notes

Reaction equation

HRID 108912 reaction equation
[CH3:25][CH2:26][OH:27].[Na+:24].[OH-:23].[OH2:22].[OH:1][CH:2]1[CH:3]([C:17](=[O:18])[O:19][CH2:20][CH3:21])[CH2:4][N:5]([C:7](=[O:8])[O:9][CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:6]1>>[OH:1][CH:2]1[CH:3]([C:17](=[O:18])[OH:19])[CH2:4][N:5]([C:7](=[O:8])[O:9][CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:6]1

Participants

6

Reactant 5

HCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 150432791-Benzyl 3-ethyl 4-hydroxypyrrolidine-1,3-dicarboxylate

Product 1

HCID 448909181-N-Cbz-4-hydroxy-beta-proline

Sources & evidence

ORD record
ord-3817228bbd9f46c1b9128844d7301d65
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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