HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[(3S,4R)-3-[(1R)-1-allyloxycarbonyloxyethyl]-4-mercapto-2-oxo-azetidin-1-yl]-2-triphenylphosphoranylideneacetic acid allyl ester → 2-[(3S,4R)-3-[(1R)-1-allyloxycarbonyloxyethyl]-4-[N-(4-allyloxycarbonylaminophenyl)-N-(allyloxycarbonyl)-glycylthio]2-oxo-azetidin-1-yl]-2-triphenylphosphoran-ylideneacetic acid allyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[(3S,4R)-3-[(1R)-1-allyloxycarbonyloxyethyl]-4-mercapto-2-oxo-azetidin-1-yl]-2-triphenylphosphoranylideneacetic acid allyl ester | HCID 14084562 | — |
| Reactant | N-(4-allyloxy-carbonylaminophenyl)-N-(allyloxycarbonyl)-glycine | HCID 86744306 | — |
| Catalyst | Silver | HCID 23954 | — |
| Product | 2-[(3S,4R)-3-[(1R)-1-allyloxycarbonyloxyethyl]-4-[N-(4-allyloxycarbonylaminophenyl)-N-(allyloxycarbonyl)-glycylthio]2-oxo-azetidin-1-yl]-2-triphenylphosphoran-ylideneacetic acid allyl ester | HCID 86744305 | — |
Reaction Steps
Analogously to Example 1, 2.67 g of N-(4-allyloxy-carbonylaminophenyl)-N-(allyloxycarbonyl)-glycine are converted with 3.5 g of the silver salt of 2-[(3S,4R)-3-[(1R)-1-allyloxycarbonyloxyethyl]-4-mercapto-2-oxo-azetidin-1-yl]-2-triphenylphosphoranylideneacetic acid allyl ester into the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04965260 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-08b186ab88d045d7a43eea7322596fd2 |
| Source note | uspto-grants-1990_10 |