Trimethylamine → HCID 15713152, compound

HRID 1089325Notes

Reaction equation

HRID 1089325 reaction equation
[CH3:1][C:2]1([CH3:12])[NH:6][CH2:5][CH:4]([CH2:7][O:8][CH:9]([CH3:11])[CH3:10])[O:3]1.[Cl:13][C:14]([Cl:19])([Cl:18])[C:15](Cl)=[O:16].CN(C)C>C1C=CC=CC=1>[CH3:1][C:2]1([CH3:12])[N:6]([C:15](=[O:16])[C:14]([Cl:19])([Cl:18])[Cl:13])[CH2:5][CH:4]([CH2:7][O:8][CH:9]([CH3:10])[CH3:11])[O:3]1

Participants

5

Reactant 3

HCID 1146TrimethylamineHCID 6420Trichloroacetyl chlorideHCID 15713151HCID 15713151, compound

Product 1

HCID 15713152HCID 15713152, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

To 20.8 milliliters of 25 percent w/v, 2,2-dimethyl-5-isopropoxymethyl oxazolidine solution in 50 milliliters of benzene was added 5.5 grams of trichloroacetyl chloride. To this solution was added dropwise with cooling, 3.1 grams of trimethylamine. After washing with water, drying and removal of the benzene in vacuo, there was obtained 8.1 grams of the title compound, nD30 1.4603. Analytical data supports the structure.

Workup

  1. additionTo this solution was added dropwise
  2. temperaturewith cooling
  3. washAfter washing with water
  4. customdrying
  5. customremoval of the benzene in vacuo

Sources & evidence

ORD record
ord-6fce75e008c246ec8f56f066e4ad7b9f
Source dataset
uspto-grants-1990_10
Patent number
US04965368

Reaction notes

Loading…