Etidronic Acid → ZINC oxide ZINC etidronate

Participants

Reaction Steps

First, 1030 g of a solution of etidronic acid (206 g as etidronic acid) was heated to 70° C. and 2035 g of a zinc oxide slurry (407 g as zinc oxide) held at 70° C. was added dropwise over about 2 hours with stirring. The mol ratio of zinc oxide to etidronic acid was 5/1. This slurry was stirred at 60° to 70° C. for 5 hours and, then, cooled to room temperature. The slurry was filtered and the dehydrated cake was washed with distilled water 3 to 5 times and, then, subjected to dehydration, drying and pulverization to give a zinc oxide/zinc etidronate composition.

Provenance & Evidence