HCID 14536735, compound → HCID 14536738, compound

HRID 1089430Notes

Reaction equation

HRID 1089430 reaction equation
[C:1]([NH:4][CH2:5][CH2:6][N:7]1[C:11]([CH3:12])=[CH:10][C:9]([C:13]([O:15]CC2C=CC=CC=2)=[O:14])=[C:8]1[CH3:23])(=[O:3])[CH3:2]>C(O)C>[C:1]([NH:4][CH2:5][CH2:6][N:7]1[C:11]([CH3:12])=[CH:10][C:9]([C:13]([OH:15])=[O:14])=[C:8]1[CH3:23])(=[O:3])[CH3:2]

Participants

3

Reactant 1

HCID 14536735HCID 14536735, compound

Product 1

HCID 14536738HCID 14536738, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.4 g (7.6 mmol) of benzyl 1-(2-acetylaminoethyl)-2,5-dimethylpyrrole-3-carboxylate from Example 3 are dissolved in 200 ml of ethanol and hydrogenated in the presence of 0.5 g of 10% strength Pd-on-charcoal at room temperature. After the mixture has been concentrated, the resulting solid is stirred with methylene chloride and filtered off with suction.

Workup

  1. concentrationAfter the mixture has been concentrated
  2. filtrationfiltered off with suction

Sources & evidence

ORD record
ord-14d30af93e8f4ac49fafe16204dfe1e9
Source dataset
uspto-grants-1990_10
Patent number
US04966901

Reaction notes

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