HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyclohexylacetaldehyde → 4-(2-Cyclohexylethyl)-9-(1H-imidazol-1-yl)-3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyclohexylacetaldehyde | HCID 316627 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | 9-(1H-imidazol-1-yl)-3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonine | HCID 14856364 | — |
| Product | 4-(2-Cyclohexylethyl)-9-(1H-imidazol-1-yl)-3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonine | HCID 14856376 | — |
Reaction Steps
In a manner similar to example 4, react 9-(1H-imidazol-1-yl)-3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonine with cyclohexaneacetaldehyde and NaBH3CN to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04966967 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-d049d0d142cd4d9a9791bbf8d03922cd |
| Source note | uspto-grants-1990_10 |