Tetralin → (2,2,2-trifluoroethyl)benzene

Temperature

200 °C

In distillation apparatus, a mixture of 50 g (0.1 mol) of (1-phenyl-2,2,2-trifluoroethoxy)tris(diethylamino)phosphonium bromide according to Example 1 and 40 g (0.3 mol) of tetrahydronaphthalene were heated for 2 hours at about 200° C. After about an hour, the reaction product was slowly distilled off through a small column, in which the boiling temperature at the column head did not exceed 140° C. The remaining product was distilled off from the reaction mixture at 40 mbar, after the reaction was completed. Repeated distillation of the combined fractions gave 10.2 g (64% of yield) of (2,2,2-trifluoroethyl)benzene of b.p. 71° to 72° C./100 mbar.

1. distillationIn distillation apparatus
2. waitAfter about an hour
3. distillationthe reaction product was slowly distilled off through a small column, in which the boiling temperature at the column head
4. customdid not exceed 140° C
5. distillationThe remaining product was distilled off from the reaction mixture at 40 mbar
6. distillationRepeated distillation of the combined fractions

ORD record

ord-24945e6372334dc9bcd7f1f04ef9082f

Source dataset

uspto-grants-1990_10

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04966987