3-Chloro-2-methyl-1-propene → HCID 22159646, compound

Participants

Reaction Steps

93 g of NaOH, 12 g of Nal and 6.8 g of Emkapol 400 (polyethyleneglycol) were charged into a 1 l three-neck flask. 100 g of methylisopropyl ketone were added and, at 50°, 290 g of methallyl chloride. The mixture was heated to reflux for 4 h and then hydrolysed with 200 ml of water. The reaction product was washed to neutrality and distilled to provide 69.6 g of raw product (B. p. 56°-65°/5.0×103Pa). Distillation of this raw product on a Widmer column gave 44.5 g of the desired ketone.

Provenance & Evidence