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HRID1089628

反应详情

EQUATION

反应方程式

HRID 1089628 的结构方程式

REACTANTS

反应物

2
结构：CO
HCID887

Methanol

CH4O

结构：CC(=O)OCC1=C[C@@H]2OC(=O)C3=CO[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]1[C@@H]32
HCID84298

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]2C(CO)=C[C@H](O)[C@H]12
HCID6325021

Deacetylasperulosidic acid methyl ester

C17H24O11

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

Asperuloside (1.0 g) was dissolved in distilled water (10 ml) and adjusted to pH=10 by adding a small amount of a saturated solution of BaO in methanol. This solution was allowed to stand for a few minutes to become cloudy white, which, after neutralization and concentration, was treated by silica gel column chromatography (Waco Gel C-300, 50 g, solvent: chloroform-methanol system). Silica gel column chromatography gave deacetyl asperulosidic acid methyl ester having Rf value=0.79 (chloroform-methanol-water=6:6:1, visualized with 50(%)-sulfuric acid) on TLC, as white needles (1.80 mg).

WORKUP

后处理

  1. waitto stand for a few minutes
  2. concentrationwhich, after neutralization and concentration
  3. additionwas treated by silica gel column chromatography (Waco Gel C-300, 50 g, solvent: chloroform-methanol system)