2-Fluorotoluene → 1-(Dimethoxymethyl)-2-fluorobenzene

HRID 1089636Notes

Reaction equation

HRID 1089636 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH3:8].[C:9](OC(=O)C)(=[O:11])C.[CH3:16][O:17]S([O-])(=O)=O.C([N+](CC)(CC)C)C>C(O)(=O)C>[CH3:9][O:11][CH:8]([O:17][CH3:16])[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[F:1]

Participants

5

Reactant 3

HCID 72412-FluorotolueneHCID 7918Acetic AnhydrideHCID 119903537588-22-9

Product 1

HCID 114267321-(Dimethoxymethyl)-2-fluorobenzene

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Electrolyte: 1013 g (9.206 mol) of 2-fluorotoluene, 675 g of acetic anhydride, 338 g of triethylmethylammonium methyl sulfate and 4727 g of acetic acid

Sources & evidence

ORD record
ord-fe0be132d8e74a17925742fd3861a47f
Source dataset
uspto-grants-1992_01
Patent number
US05078838

Reaction notes

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