HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → 2-Phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 2-Phenoxy-2-oxo-6-iodomethyl-1,2-oxaphosphorinane | HCID 19793129 | — |
| Catalyst | Tetrabutylammonium Bromide | HCID 74236 | — |
| Solvent | Benzene dimethylformamide | HCID 19608675 | — |
| Product | 2-Phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane | HCID 19793120 | 96% |
Reaction Steps
A suspension containing two equivalents of sodium azide, one equivalent of the above-prepared iodonated oxaphosphorinane and a catalytic amount of about 0.1 equivalent of tetrabutylammonium bromide in benzene/DMF (1:1) was heated to 60-80 degrees C. for 16 hours to produce 2-phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane in 96 percent yield as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05079152 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-aec982f9bed9410e82658bd88d6183e0 |
| Source note | uspto-grants-1992_01 |