HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol, 2-chloro-, 1-(4-methylbenzenesulfonate) → HCID 19915736, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol, 2-chloro-, 1-(4-methylbenzenesulfonate) | HCID 6639 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Hydroxybenzamide | HCID 342403 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 19915736 | HCID 19915736 | 70.6% |
Reaction Steps
To a solution of 3-hydroxybenzamide (21.6 g) in methyl ethyl ketone ("MEK") was added 2-chloroethyl p-toluenesulphonate (55.46 g) and potassium carbonate (16.0 g). After starting at reflux for 6 hours, the resultant mixture was poured onto water and a colourless solid filtered off. Crystallisation from ethanol gave the title compound, (22.2 g), m.p. 125°-126°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05079248 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-472d978851664a56b66f705a7090d1d0 |
| Source note | uspto-grants-1992_01 |