1H-Imidazole-1-propanamine → HCID 86745369, compound

HRID 1089746Notes

Reaction equation

HRID 1089746 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][N:8]2[C:16]3[C:11]4[C:12](=[CH:17][CH:18]=[CH:19][C:10]=4[C:9]2=S)[CH:13]=[CH:14][CH:15]=3)[CH:2]=1.[N:21]1([CH2:26][CH2:27][CH2:28][NH2:29])[CH:25]=[CH:24][N:23]=[CH:22]1>C(O)C>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][N:8]2[C:16]3[C:11]4[C:12](=[CH:17][CH:18]=[CH:19][C:10]=4[C:9]2=[C:28]([NH2:29])[CH2:27][CH2:26][N:21]2[CH:25]=[CH:24][N:23]=[CH:22]2)[CH:13]=[CH:14][CH:15]=3)[CH:2]=1

Participants

4

Reactant 2

HCID 787361H-Imidazole-1-propanamineHCID 15023416HCID 15023416, compound

Product 1

HCID 86745369HCID 86745369, compoundYield 73.8%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2.75 g of 1-(3-pyridinylmethyl)-benz[cd]indole-2(1H)-thione (Cg), 1.4 g of 1H-imidazole -1-propanamine, 150 ml of ethyl alcohol and 3.5 g of mercuric acetate is reacted as described in Example 3, giving 2.7 g of the desired product, mp. 139°-141° C.

Workup

  1. customis reacted

Sources & evidence

ORD record
ord-f5a260bbf53d4adfb2218c8fa97dbb30
Source dataset
uspto-grants-1992_01
Patent number
US05079247

Reaction notes

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