1H-Imidazole-1-propanamine → HCID 9946824, compound

HRID 1089749Notes

Reaction equation

HRID 1089749 reaction equation
S=[C:2]1[C:10]2[CH:11]=[CH:12][CH:13]=[C:8]3[C:9]=2[C:4](=[CH:5][CH:6]=[CH:7]3)[N:3]1[CH2:14][CH2:15][CH2:16][CH2:17][C:18]#[N:19].[N:20]1([CH2:25][CH2:26][CH2:27][NH2:28])[CH:24]=[CH:23][N:22]=[CH:21]1>C(O)C>[N:20]1([CH2:25][CH2:26][CH2:27][N:28]=[C:2]2[C:10]3[CH:11]=[CH:12][CH:13]=[C:8]4[C:9]=3[C:4](=[CH:5][CH:6]=[CH:7]4)[N:3]2[CH2:14][CH2:15][CH2:16][CH2:17][C:18]#[N:19])[CH:24]=[CH:23][N:22]=[CH:21]1

Participants

4

Reactant 2

HCID 787361H-Imidazole-1-propanamineHCID 15023421HCID 15023421, compound

Product 1

HCID 9946824HCID 9946824, compoundYield 80.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 4.0 g of 2-thioxobenz[cd]indole-1(2H)-pentanenitrile (Cl), 1.88 g of 1H-imidazole-1-propanamine, 100 ml of ethyl alcohol, and 4.8 g of mercuric acetate is reacted as described in Example 3, giving 4.3 g of the desired product, mp. 76°-78.5° C.

Workup

  1. customis reacted

Sources & evidence

ORD record
ord-85ffe4f99e52491fb9e2828ebf444dcd
Source dataset
uspto-grants-1992_01
Patent number
US05079247

Reaction notes

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