1H-Imidazole-1-propanamine → HCID 10135646, compound

HRID 1089750Notes

Reaction equation

HRID 1089750 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][N:9]2[C:17]3[C:12]4[C:13](=[CH:18][CH:19]=[CH:20][C:11]=4[C:10]2=S)[CH:14]=[CH:15][CH:16]=3)=[CH:4][CH:3]=1.[N:22]1([CH2:27][CH2:28][CH2:29][NH2:30])[CH:26]=[CH:25][N:24]=[CH:23]1>C(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][N:9]2[C:17]3[C:12]4[C:13](=[CH:18][CH:19]=[CH:20][C:11]=4[C:10]2=[N:30][CH2:29][CH2:28][CH2:27][N:22]2[CH:26]=[CH:25][N:24]=[CH:23]2)[CH:14]=[CH:15][CH:16]=3)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 787361H-Imidazole-1-propanamineHCID 15023424HCID 15023424, compound

Product 1

HCID 10135646HCID 10135646, compoundYield 34%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2.5 g of 1-p-chlorophenylmethylbenz[cd]indole-2(1H)-thione (Cp), 1.1 g of 1H-imidazole -1-propanamine, 200 ml of ethyl alcohol, and 2.6 g of mercuric acetate is reacted as described in Example 3, giving 1.1 g of the desired product, mp. 90°-91° C.

Workup

  1. customis reacted

Sources & evidence

ORD record
ord-28f74e9e17f243cba172da11bf3349e2
Source dataset
uspto-grants-1992_01
Patent number
US05079247

Reaction notes

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