HRID1089762

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID15020358

4-[(4-Fluorophenyl)(phenyl)methylidene]piperidine

C18H18FN

HCID19915752

未命名化合物

PRODUCTS

生成物

结构：Cl.Cl.O=C1CN(Cc2ccccn2)CC(=O)N1CCCN1CCC(=C(c2ccccc2)c2ccc(F)cc2)CC1

HCID67895758

未命名化合物

PROCEDURE

实验过程

This compound was prepared from 4-[(4-fluorophenyl)phenylmethylene]piperidine and 1-(3-chloropropyl)-4-(2-pyridylmethyl)-2,6-piperazinedione according to the process described in Example 6, Stage E.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-16487729fcc44cbdb8a080b42d73fa61
来源数据集: uspto-grants-1992_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05079249
来源说明: uspto-grants-1992_01

反应 SMILES

[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[C:9]2[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]2)=[CH:4][CH:3]=1.[Cl:21][CH2:22][CH2:23][CH2:24][N:25]1[C:30](=[O:31])[CH2:29][N:28]([CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][N:34]=2)[CH2:27][C:26]1=[O:39]>>[ClH:21].[ClH:21].[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[C:9]2[CH2:10][CH2:11][N:12]([CH2:22][CH2:23][CH2:24][N:25]3[C:30](=[O:31])[CH2:29][N:28]([CH2:32][C:33]4[CH:38]=[CH:37][CH:36]=[CH:35][N:34]=4)[CH2:27][C:26]3=[O:39])[CH2:13][CH2:14]2)=[CH:6][CH:7]=1