4-(Bis(4-fluorophenyl)methylene)piperidine → HCID 178432284, compound

HRID 1089763Notes

Reaction equation

HRID 1089763 reaction equation
[Cl:1][CH2:2][CH2:3][C:4]1[C:5]([CH3:16])=[N:6][C:7]2[N:8]([CH:11]=[N:12][C:13]=2[C:14]#[N:15])[C:9]=1[OH:10].[F:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]([C:31]2[CH:36]=[CH:35][C:34]([F:37])=[CH:33][CH:32]=2)=[C:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)=[CH:20][CH:19]=1>>[ClH:1].[F:37][C:34]1[CH:35]=[CH:36][C:31]([C:24]([C:21]2[CH:20]=[CH:19][C:18]([F:17])=[CH:23][CH:22]=2)=[C:25]2[CH2:30][CH2:29][N:28]([CH2:2][CH2:3][C:4]3[C:5]([CH3:16])=[N:6][C:7]4[N:8]([CH:11]=[N:12][C:13]=4[C:14]#[N:15])[C:9]=3[OH:10])[CH2:27][CH2:26]2)=[CH:32][CH:33]=1

Participants

3

Reactant 2

HCID 27244364-(Bis(4-fluorophenyl)methylene)piperidineHCID 178432280HCID 178432280, compound

Product 1

HCID 178432284HCID 178432284, compound

Procedure

This compound was prepared from 3-chloroethyl-8-cyano-4-hydroxy-2-methylimidazo[1,5-a]pyrimidine and 4-[bis(4-fluorophenyl)methylene]piperidine according to the process described in Example 4, Stage B.

Sources & evidence

ORD record
ord-d6ebf406b762440d9ed8f75b522758c1
Source dataset
uspto-grants-1992_01
Patent number
US05079249

Reaction notes

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