HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 4-(3,4-Dihydroxyphenyl)-8-methyl-1,2,3,4-tetrahydroisoquinoline hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 4-(3,4-Dimethoxyphenyl)-8-methyl-1,2,3,4-tetrahydroisoquinoline | HCID 10517097 | — |
| Product | 4-(3,4-Dihydroxyphenyl)-8-methyl-1,2,3,4-tetrahydroisoquinoline hydrobromide | HCID 14719552 | — |
Reaction Steps
To 420 mg of 4-(3,4-dimethoxyphenyl)-8-methyl-1,-2,3,4-tetrahydroisoquinoline, was added 48% hydrobromic acid, and the mixture was heated under reflux for 3 hours. After about 10 minutes, the crystals become separated out. The reaction mixture was cooled, and the crystals were collected by filtration, giving 420 mg of 4-(3,4-dihydroxyphenyl)-8-methyl-1,2,3,4-tetrahydroisoquinoline hydrobromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05079256 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-6259b20b65084715a82c162a18778c04 |
| Source note | uspto-grants-1992_01 |