Sodium Dithionite → HCID 53969144, compound

HRID 1089819Notes

Reaction equation

HRID 1089819 reaction equation
[CH3:1][O:2][C:3]1[C:4](=[O:24])[C:5]2[C:6]([C:20]([O:22][CH3:23])=[O:21])=[C:7]([CH:14]=[CH:15][C:16]([O:18][CH3:19])=[O:17])[N:8]([CH3:13])[C:9]=2[C:10](=[O:12])[CH:11]=1.[O-]S(S([O-])=O)=O.[Na+].[Na+]>C(Cl)(Cl)Cl.C(O)C>[OH:24][C:4]1[C:3]([O:2][CH3:1])=[CH:11][C:10]([OH:12])=[C:9]2[C:5]=1[C:6]([C:20]([O:22][CH3:23])=[O:21])=[C:7]([CH:14]=[CH:15][C:16]([O:18][CH3:19])=[O:17])[N:8]2[CH3:13]

Participants

5

Reactant 2

HCID 24489Sodium DithioniteHCID 53815835HCID 53815835, compound

Product 1

HCID 53969144HCID 53969144, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 6212ChloroformSolvent

Procedure

Methyl 5-methoxy-3-methoxycarbonyl-N-methyl-4,7-dioxo-2-indoleacrylate (18) (6.64 g, 20 mmol) was dissolved in a mixture of chloroform (600 ml) and ethanol (215 ml). The reduction was carried out on stirring with an aqueous solution (260 ml) of Na2S2O4 (42 g) at room temperature for 30 minutes.

Sources & evidence

ORD record
ord-5776ac3db9fc4121938ccad7e71038a8
Source dataset
uspto-grants-1992_01
Patent number
US05079257

Reaction notes

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