HCID 4048528, compound → 3-Pyridinecarboxamide, 2-methoxy-N,N-bis(1-methylethyl)-

HRID 1089905Notes

Reaction equation

Cl[C:2]1[C:7]([C:8]([N:10]([CH:14]([CH3:16])[CH3:15])[CH:11]([CH3:13])[CH3:12])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.[CH3:17][O-:18].[Na+]>>[CH:11]([N:10]([CH:14]([CH3:16])[CH3:15])[C:8]([C:7]1[C:2]([O:18][CH3:17])=[N:3][CH:4]=[CH:5][CH:6]=1)=[O:9])([CH3:13])[CH3:12]

Participants

Reactant 2

HCID 4048528HCID 4048528, compound

HCID 10942334Sodium Methoxide

Product 1

HCID 109990003-Pyridinecarboxamide, 2-methoxy-N,N-bis(1-methylethyl)-Yield 98%

Procedure

In a similar manner but by refluxing 2-chloro 3-diisopropylaminocarbonyl pyridine and sodium methylate for 45 hours, 3-diisopropylaminocarbonyl 2-methoxy pyridine is obtained.

Sources & evidence

ORD record: ord-5dd27c2913d24e228681b3ecb54617b9
Source dataset: uspto-grants-1992_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05079363

Reaction notes

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