Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | N,N,N',N'-Tetramethylethylenediamine | HCID 8037 | — |
| Reactant | HCID 14476644 | HCID 14476644 | — |
| Reactant | HCID 178418306 | HCID 178418306 | — |
| Solvent | Pentane | HCID 8003 | — |
| Product | HCID 178506754 | HCID 178506754 | — |
Reaction Steps
Over a period of several minutes 0.0075 mole of tert.butyllithium (4.41 ml of a 1.7 molar solution in pentane) are added to a solution of 1.041 g (0.005 mole) of 3-diethylaminocarbonyl 2-methoxy pyridine and 1.13 ml (0.0075 mole) of tetramethylethylenediamine in 15 ml of tetrahydrofuran cooled to -80° C. while the temperature is maintained below -80° C. After 20 minutes at this temperature, an orange-colored solution of 3-diethylaminocarbonyl 4-lithio 3-methoxy pyridine is obtained which is used as such.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05079363 |
|---|
| Source dataset | uspto-grants-1992_01 |
|---|
| ORD ID | ord-a07c6eae29374982a18742f213b1b50b |
|---|
| Source note | uspto-grants-1992_01 |
|---|
