HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N,N',N'-Tetramethylethylenediamine → (1-Tert.butoxycarbonyl 5-aza 2-indolyl) (3-diethylaminocarbonyl 2-methoxy 4-pyridyl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N,N',N'-Tetramethylethylenediamine | HCID 8037 | — |
| Reactant | 2,2,6,6-Tetramethylpiperidine | HCID 13035 | — |
| Reactant | N,N-Diethyl-4-formyl-2-methoxynicotinamide | HCID 11806629 | — |
| Reactant | HCID 178506646 | HCID 178506646 | — |
| Product | (1-Tert.butoxycarbonyl 5-aza 2-indolyl) (3-diethylaminocarbonyl 2-methoxy 4-pyridyl)methanol | HCID 14476670 | — |
Reaction Steps
Starting from 1-tert.butoxycarbonyl 2-lithio 5-aza indole and 3-diethylaminocarbonyl 4-formyl 2-methoxy pyridine as reagent with electrophilic character, prepared according to paragraph b (stabilization reagent: tetramethylethylenediamine; amine: 2,2,6,6-tetramethylpiperidine).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05079363 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-543a3a3d03ff48d59fe23302b7790343 |
| Source note | uspto-grants-1992_01 |