Epichlorohydrin → HCID 53731568, compound

HRID 1089984Notes

Reaction equation

HRID 1089984 reaction equation
[CH2:1]([CH:3]1[O:5][CH2:4]1)[Cl:2].[CH3:6][O:7][C:8]1[CH:15]=[CH:14][C:11]([CH2:12][SH:13])=[CH:10][CH:9]=1>>[Cl:2][CH2:1][CH:3]([OH:5])[CH2:4][S:13][CH2:12][C:11]1[CH:14]=[CH:15][C:8]([O:7][CH3:6])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 7835EpichlorohydrinHCID 804074-Methoxy-alpha-toluenethiol

Product 1

HCID 53731568HCID 53731568, compound

Conditions

Temperature
125 °C

Procedure

2.78 ml of epichlorohydrin and 2.78 ml of p-methoxybenzylmercaptan were heated with stirring at 120 to 130° C. for three hours. After cooling, the product was purified by column chromatography using 100 g of silica gel and benzene as an eluent to obtain 1.44 g of the objective compound.

Workup

  1. temperatureAfter cooling
  2. customthe product was purified by column chromatography

Sources & evidence

ORD record
ord-93e2a5cacc16448e850011bdfcd1d0b4
Source dataset
uspto-grants-1992_01
Patent number
US05079357

Reaction notes

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