5,6,7,8-Tetrahydro-2-naphthol → HCID 19914429, compound

HRID 1090057Notes

Reaction equation

HRID 1090057 reaction equation
[OH-].[K+].[CH:3]1[C:12]2[CH2:11][CH2:10][CH2:9][CH2:8][C:7]=2[CH:6]=[CH:5][C:4]=1[OH:13].[CH3:14][C:15]1[CH:16]=[C:17]([CH:22]=[CH:23][CH:24]=1)[O:18][CH2:19][CH2:20]Cl>O>[CH3:14][C:15]1[CH:16]=[C:17]([CH:22]=[CH:23][CH:24]=1)[O:18][CH2:19][CH2:20][O:13][C:4]1[CH:5]=[CH:6][C:7]2[CH2:8][CH2:9][CH2:10][CH2:11][C:12]=2[CH:3]=1

Participants

5

Reactant 3

HCID 143055,6,7,8-Tetrahydro-2-naphtholHCID 14797Potassium HydroxideHCID 9505349HCID 9505349, compound

Product 1

HCID 19914429HCID 19914429, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4.0 g (0.06 mol) of 85% potassium hydroxide was dissolved in 25 g of distilled water and 7.4 g (0.05 mol) of 5,6,7,8-tetrahydro-β-naphthol was dissolved in the formed solution. 8.5 g (0.05 mol) of 2-(3-methylphenoxy)ethyl chloride was added to the solution and the mixture was stirred under reflux for 3 h.

Workup

  1. temperatureunder reflux for 3 h.

Sources & evidence

ORD record
ord-38a6530c73614189909be25893fbc6ec
Source dataset
uspto-grants-1992_01
Patent number
US05081099

Reaction notes

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