Methanol → 1-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

HRID 109006Notes

Reaction equation

HRID 109006 reaction equation
[C:1](=[O:2])([CH3:3])[O:4][CH2:5][CH:6]1[CH:7]([F:20])[CH2:8][CH:9]([n:11]2[c:12](=[O:13])[nH:14][c:15](=[O:16])[c:17]([CH3:18])[cH:19]2)[O:10]1.[CH3:21][O-:22].[CH3:24][OH:25].[Na+:23]>>[OH:4][CH2:5][CH:6]1[CH:7]([F:20])[CH2:8][CH:9]([n:11]2[c:12](=[O:13])[nH:14][c:15](=[O:16])[c:17]([CH3:18])[cH:19]2)[O:10]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 3826051MethoxideHCID 13321618[3-Fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate

Product 1

HCID 2842401-[4-Fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Sources & evidence

ORD record
ord-6ea6a4a3e6bd4b46bb0b947da5b99974
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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