HCID 19027057, compound → HCID 67833605, compound

Participants

Reaction Steps

A suspension of 5-ethoxalylamino-8-ethoxalylaminosulfonyl-1,2,3,4-tetrahydro-6-nitronaphthalene (0.61 g, 1.3 mmol) in 100 ml of ethanol was hydrogenated at room temperature and atmospheric pressure in the presence of 60 mg of 5% platinum on carbon. After the theoretical absorption, the mixture was filtered and the filtrate was evaporated to dryness. The crude product (0.51g) was triturated with 50 ml of water, filtered off and then washed with water and a small amount of cold ethanol affording 0.28 g (53%) of the title compound. M.p. 267° C. decomp. (DSC); IR (KBr): 1725 cm-1 ; 1H-NMR (DMSO-d6): 1.23 (t,J=7Hz, 3H, CH3), 1.57-1.93 (m, 4H, 2CH2), 2.63-3.20 (m, 4H, 2CH2), 4.20 (q,J=7Hz, 2H, CH2), 7.98 (s, 1H, ArH), 11.5 (broad s, 1H, NH, only one exchangeable proton could be seen).

Provenance & Evidence