HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanecarbonyl chloride → HCID 15675287, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanecarbonyl chloride | HCID 77637 | — |
| Reactant | HCID 15675273 | HCID 15675273 | — |
| Reactant | 1-(2-Amino-4-ethoxy-5-methoxyphenyl)ethan-1-one | HCID 15675275 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 15675287 | HCID 15675287 | 101.5% |
Reaction Steps
2-Acetyl-5-ethoxy-4-metoxyaniline (550 mg), cyclopropylcarbonyl chloride (410 mg) and triethylamine (530 mg) were reacted in the same manner as in the preparation of compound 95 to give N-cyclopropylcarbonyl-2-acetyl-5-ethoxy-4-methoxyaniline (740 mg). The compound (600 mg) and potassium t-butoxide (1.18 g) were reacted in the same manner as in the preparation of compound 95 to obtain 2-cyclopropyl-7-ethoxy-6-methoxy-4(1H)-quinolone (compound 98, 330 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081121 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-eb85d842740c4c28b58a8ac911858fef |
| Source note | uspto-grants-1992_01 |