HuagongsheHuagongshe Chemistry Print Report · For research reference only
2'-Aminoacetophenone → N-(2-Acetylphenyl)thiophene-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2'-Aminoacetophenone | HCID 11086 | — |
| Reactant | 2-Thiophenecarbonyl chloride | HCID 78928 | — |
| Reactant | HCID 15675273 | HCID 15675273 | — |
| Product | N-(2-Acetylphenyl)thiophene-2-carboxamide | HCID 218728 | 85.4% |
Reaction Steps
2-Acetylaniline (2.0 g) and 2-thenoyl chloride (3.2 g) were condensed in the same manner as in the preparation of compound 95 to obtain N-(2-thenoyl)-2-acetylaniline (3.1 g). The compound (2.0 g) and potassium t-butoxide (9.1 g) were reacted in the same manner as in the preparation of compound 95 to obtain 2-(2-thienyl)-4(1H)-quinolone (compound 100, 310 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081121 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-b3f0dcdd381747dcba4763989c2ebc63 |
| Source note | uspto-grants-1992_01 |