Sodium Hydroxide → HCID 15713267, compound

HRID 1090169Notes

Reaction equation

HRID 1090169 reaction equation
[CH:1]([N:3]1[CH:8]([C:9]([O:11]CC)=[O:10])[CH2:7][CH:6]([CH3:14])[CH2:5][C:4]1([OH:20])[C:15]([O:17]CC)=[O:16])=[O:2].[OH-].[Na+]>C(O)C>[CH:1]([N:3]1[CH:8]([C:9]([OH:11])=[O:10])[CH2:7][CH:6]([CH3:14])[CH2:5][C:4]1([OH:20])[C:15]([OH:17])=[O:16])=[O:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 15713265HCID 15713265, compound

Product 1

HCID 15713267HCID 15713267, compoundYield 134.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 143 mg of the product of Example 18, 2 ml of ethanol and 1 ml of N sodium hydroxide was stirred for 15 hours at ambient temperature to obtain 155 mg of product which was taken up in water, filtered and lyophilized to obtain 146 mg of the desired product with a Rf=0.35 (butanol-acetic acid-ethanol 4-2-2).

Sources & evidence

ORD record
ord-492119e593fa48c4b1a57fb4ff943520
Source dataset
uspto-grants-1992_01
Patent number
US05081135

Reaction notes

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